Let's first examine the differences between these two solvents. Whereas organic ethanol is made from organic resources, 200 Proof Grain Alcohol is a high-proof ethanol obtained from grain sources. Both are highly valued for their strength and purity, which makes them perfect for use in herbal tinctures.Let's first examine the differences between these two solvents. Whereas organic ethanol is made from organic resources, 200 Proof Grain Alcohol is a high-proof ethanol obtained from grain sources. Both are highly valued for their strength and purity, which makes them perfect for use in herbal tinctures.